Ailux

Contact us
News

Ailux Announces Posters at American College of Rheumatology (ACR) Convergence 2025

Ailux Announces Posters at American College of Rheumatology (ACR) Convergence 2025

SHANGHAI (CHINA) and SOMERVILLE, MA (US) — October 27, 2025 — Ailux, an innovator in AI-powered biologics and a subsidiary of XtalPi (2228.HK), a global leader in AI drug discovery, today announced scientific presentations at the ACR Convergence 2025.

Ailux leveraged an AI-powered antibody discovery platform to precisely design two therapeutic candidates with desired properties for the treatment of inflammatory or autoimmune diseases.

“Our first-in-class FcRn × albumin bispecific antibody combines potent FcRn blockade with extended half-life, offering a long-acting treatment that could transform the patient journey with autoantibody diseases,” said Alex Li, CEO of Ailux. “Our half-life extended TL1A antibody shows potent anti-inflammatory activity and reduced immunogenicity risk with a unique mechanism of action, demonstrating its potential as a safer, more durable therapy, and as a promising backbone in next-generation multispecifics.”

The posters will be available for viewing during the ACR Convergence 2025, with the below details:

Title: A Novel FcRn × Albumin Bispecific Antibody Demonstrates Extended Half-life and Deep IgG Reduction in Preclinical Mouse Models

Title: Preclinical Development of a Novel TL1A-Targeting Antibody with Extended Half-life and Low Immunogenicity Risk for the Treatment of Inflammatory Diseases

Full poster session details can be accessed via the ACR program.

About Ailux
Ailux is a biologics innovation company dedicated to developing advanced biotherapeutics with AI-powered solutions. As XtalPi’s dedicated biologics platform, Ailux integrates proprietary computational models with state-of-the-art wet lab capabilities to tackle previously undruggable targets and design molecules with novel therapeutic profiles. With a global team of more than 100 members, Ailux partners with leading biopharmaceutical companies to translate cutting-edge science into transformative medicines.

For more information, visit ailuxbio.com.
To learn more about collaboration and partnerships, contact bd@ailuxbio.com.

Privacy Settings
We use cookies to enhance your experience while using our website. If you are using our Services via a browser you can restrict, block or remove cookies through your web browser settings. We also use content and scripts from third parties that may use tracking technologies. You can selectively provide your consent below to allow such third party embeds. For complete information about the cookies we use, data we collect and how we process them, please check our Privacy Policy
Youtube
Consent to display content from - Youtube
Vimeo
Consent to display content from - Vimeo
Google Maps
Consent to display content from - Google
Spotify
Consent to display content from - Spotify
Sound Cloud
Consent to display content from - Sound