Ailux’s AI-powered biologics pipeline is focused on developing differentiated and convenient therapies for underserved patients.
Ongoing advances across our platform continue to unlock new possibilities for future therapeutic innovation.
IMMUNOLOGY AND INFLAMMATION
DISCOVERY
LEAD OPTIMIZATION
PRECLINICAL
IND-ENABLING
PHASE 1/2
ALX001
TL1A/IL-23p19
IND 2027
ALX001 is a potentially best-in-class, AI-enabled bispecific antibody designed to simultaneously block two key drivers (TL1A/IL-23p19) of inflammatory bowel disease (IBD). Its novel mechanism of action supports ultra-low immunogenicity risk and potent TL1A inhibition. ALX001 has the potential to deliver superior therapeutic benefits with convenient dosing for IBD patients.
ALX002
CD19/BCMA/CD3
IND 2027
ALX002 is a potentially best-in-class, AI-optimized, dual-targeted (CD19/BCMA) T-cell engager designed for the treatment of B cell-mediated autoimmune diseases. Ailux’s proprietary CD3 masking technology enables a broader therapeutic window with potential to deliver safer immune reset and convenient dosing.
ALX005
FcRn/HSA
IND 2027
ALX005 is a potentially best-in-class, long-acting FcRn-blocking antibody designed to treat IgG-mediated autoimmune diseases with less frequent dosing. Our AI-enabled design precisely achieves durable and greater IgG clearance while maintaining a favorable preclinical safety profile.
Undisclosed
TL1A-based bispecific
Ailux is developing a differentiated bispecific antibody featuring a novel and proprietary anti-TL1A mechanism. Featuring first/best-in-class potential, we look forward to deploying this new biologic in immunological diseases.
Undisclosed
IL-4Rα-based bispecific
Ailux is developing novel long-acting bispecific options that aim to raise the efficacy ceiling of Type 2 inflammatory diseases and improve dosing convenience for patients.
Undisclosed
Multiple wholly owned AI-native programs
A suite of wholly owned undisclosed AI-native programs across multiple therapeutic areas.
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